I just voted once and for KAIJU PILEDRIVER!!! Knowing how Iron Brigade played out, I think that an entire game basically based on the giant fish sequence from Psychonauts would be awesome, and I know exactly what Muir is capable of. Not as a slight against any other member of the DF team, but I love the idea of a campy monster movie game that felt a little like Iron Brigade.
I am a 360/OSX gamer. I would game on a PC if a had one, and I would absolutely love to have a PS3, but I can't afford one at this point. I am going to get Doublefine Adventure on any and every system it comes out for though. Hurray for being a $100 backer!